Colorectal cancer in asbestos cement workers in Denmark. Thorough exami nation of rats and Syrian hamsters exposed to asbestos by inhalation at levels sufficient to cause mesothelioma in both species and lung cancer in rats did not find colorectal malignancies Hesterberg et al.
Journal of the National Cancer Institute. Colon and stomach cancer mortality among automotive wood model makers. Benign adematous colon polyps are a precursor of the most common type of colon cancer in humans. Asbestos, cement, and cancer in the right part of the colon.
No polyps were produced by chronic asbestos feeding in hamsters. British Journal of Industrial Medicine 50 Notably, the intervention had no measurable effect on colorectal cancer incidence or mortality British Journal of Industrial Medicine 45 1: Selected References These references are in PubMed.
The potential role of asbestos fibers as a cofactor has not been investigated in epidemiologic or experimental studies. Evidence for excess colorectal cancer incidence among asbestos-exposed men in the Beta-Carotene and Retinol Efficacy Trial. When they were combined, the average estimate of association was 1.
The pathological effects of prolonged asbestos ingestion in rats. That is, among groups with colorectal cancer those with high exposure did not, in aggregate, have a greater risk of cancer than those with simply any exposure.
Asbestos exposure, physical activity and colon cancer: Adjustment for body mass index and dietary intake of calcium, fiber, fat, and percentage of energy from fat as potential confounders had little effect, so they were excluded from the final models.
Variations in mortality by weight amongmen and women. Mortality experience of insulation workers in the United States and Canada, Profusion throughout the lung fields of small irregular shadows was separately rated on a progressive point scale: The overall lack of consistency or of the suggestion of an association among the case-control studies even those of the highest quality and the absence of convincing dose-response relationships in either type of study design, however, weigh against causality.
In vitro approaches for determining mechanisms of toxicity and carcinogenicity by asbestos in the gastrointestinal and respiratory tracts. Mortality and cancer morbidity in cohorts of asbestos cement workers and referents.
Annals of the New York Academy of Sciences. Hodgson J, Jones R.
American Journal of Industrial Medicine 10 Mortality and cancer morbidity in cohorts of asbestos cement workers and referents.
The details of the design aspects of those studies are presented in Table C. To study work history as a risk factor, a second subcohort of 3, men was designated the work-history-eligible subcohort. Mortality of asbestos workers in England and Wales A case-control study of historically confirmed cases of colon cancer and matched neighborhood controls was conducted in Los Angeles County, California.
In univariate analyses of the male pairs, a weak association was found between asbestos exposure and colon cancer (odds ratio (OR) =95% confidence interval (Cl) –). In a case‐control study inMagnani 6 evidenced a significantly high relative risk of oesophageal cancer among naval construction labourers having been.
Asbestos and Colon Cancer: Lack of Association in a Large Case-Control Study David H. Garabrant Asbestos and Colon Cancer: Lack of Association in a Large Case-Control Study, American Journal of or other risk factors for colon cancer. A case-control study of historically confirmed cases of colon cancer and matched neighborhood.
“A Case-Control Study of the Relationship Between the Risk of Colon Cancer in Men and Exposures to Occupational Agents,” American Journal of Industrial Medicine().
Most experimental studies with rats have shown no evidence of carcinogenicity with ingested asbestos , although one study have shown some weak evidence of. Other investigators have not found an association.
In a study of British asbestos workers, Magnimo A. Asbestos exposure, physical activity and colon cancer: a case control study.
Tumori ; 79 Garabrant DH, Peters RK, Homa DM. Asbestos and colon cancer: lack of association in a large case-control study.
Am J Epidemiol ;Download